Exacerbation of Repetitive Falls Due to Atonic Seizures Following Perampanel Administration

Drop attacks, falls and atonic seizures in the Video-EEG monitoring unit

PURPOSE We set out to determine clinical and EEG features of seizures presenting with falls, epileptic drop attacks and atonia in the video EEG monitoring unit. METHODS We searched the video EEG monitoring reports over a 5-year-period for the terms "drop", "fall" and "atonic". RESULTS Seizures presenting as epileptic drop attacks, falls or atonia were found in 23/1112 (2%) admissions. About...

Adjunctive perampanel for refractory partial-onset seizures

Methods: This was a multicenter, double-blind, placebo-controlled trial (ClinicalTrials.gov identifier: NCT00699972). Patients ( 12 years, with ongoing seizures despite 1–3 AEDs) were randomized (1:1:1) to once-daily perampanel 8 mg, 12 mg, or placebo. Following baseline (6 weeks), patients entered a 19-week double-blind phase: 6-week titration (2 mg/week increments to target dose) followed by ...

Cardiac arrest due to hyperkalemia following intravenous penicillin administration.

A patient with atonic seizures mimicking transient ischemic attacks

A focal atonic seizure is a partial seizure in which the ictal manifestation consists of paresis of the extremities or muscles on one side of the body, and this phenomenon can easily be misdiagnosed as a transient ischemic attack. An 86-year-old woman visited our hospital complaining of transient right upper extremity weakness lasting for 10 min following an unusual sensation in her chest accom...

Exacerbation of Psoriasis due to Hydroxychloroquine

[email protected] Abstract Systemic Anti-malarial Drugs (SADs) are commonly used to treat autoimmune diseases and are generally considered a benign medication. SAD-induced psoriasis has been reported in the literature, but evidence is conflicting regarding the strength of the association of SAD and psoriasis exacerbations. We present a case of hydroxychloroquine-induced psoriasis exacerbat...